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Article

Somatic mutational analysis of DAX1 in testes from men with idiopathic azoospermia.

Fertility and sterility - 1 Nov 2005

Mantovani Giovanna, Mancini Mario, Gazzano Giacomo, Spada Anna, Colpi Giovanni M, Beck-Peccoz Paolo, Persani Luca

Abstract excerpt

Mutations in the orphan nuclear receptor DAX1 (NR0B1) cause X-linked adrenal hypoplasia congenital (AHC), a disorder characterized by primary adrenal failure, hypogonadotropic hypogonadism. and azoospermia. We tested the hypothesis that DAX1 somatic mutations in human testis may cause azoospermia. DAX1 sequencing analysis in 15 testicular biopsy samples from men with idiopathic nonobstructive azoospermia did not...

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Identifiers

PMID: 16275267
DOI: 10.1016/j.fertnstert.2005.05.037

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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