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Article

Hypogonadotropic hypogonadism in subjects with DAX1 mutations.

Molecular and cellular endocrinology - 22 Oct 2011

Jadhav Unmesh, Harris Rebecca M, Jameson J Larry

Abstract excerpt

DAX1 (dosage-sensitive sex reversal, adrenal hypoplasia critical region, on chromosome X, gene 1; also known as NROB1, nuclear receptor subfamily 0, group B, member 1) encodes a nuclear receptor that is expressed in embryonic stem (ES) cells, steroidogenic tissues (gonads, adrenals), the ventromedial hypothalamus (VMH), and pituitary gonadotropes. Humans with DAX1 mutations develop an X-linked syndrome referred...

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Identifiers

PMID: 21672607
DOI: 10.1016/j.mce.2011.04.017
PMCID: PMC3185185

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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