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Article

Genetic polymorphisms and multifactorial diseases: facts and fallacies revealed by the glucocorticoid receptor gene.

Trends in endocrinology and metabolism: TEM - 1 Dec 2005

van Rossum Elisabeth F C, Russcher Henk, Lamberts Steven W J

Abstract excerpt

In recent years enormous progress in determining the sequence of the human genome has led to a rapid development of research into polymorphisms in genes involved in complex diseases. It is clear, however, that there are important limitations in many of these association studies. Problems with reliable and reproducible phenotyping, the number of individuals studied, racial heterogeneity, population stratification...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 16275120
DOI: 10.1016/j.tem.2005.10.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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