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Article

VKORC1 haplotypes and their impact on the inter-individual and inter-ethnical variability of oral anticoagulation.

Thrombosis and haemostasis - 1 Oct 2005

Geisen Christof, Watzka Matthias, Sittinger Katja, Steffens Michael, Daugela Laurynas, Seifried Erhard, Müller Clemens R, Wienker Thomas F, Oldenburg Johannes

Abstract excerpt

In order to elucidate the role of VCORC1 sequence variants in warfarin sensitivity, we established a complete SNP map of the VKORC1 gene locus in 200 blood donors from Western Germany. Nearly all of the genetic variability of the VKORC1 gene in Europeans is reflected by three main haplotypes. Recently described polymorphisms associated with low warfarin dose requirement (dbSNP:rs9934438; dbSNP:rs17878363) were...

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Source

Identifiers

PMID: 16270629
DOI: 10.1160/TH05-04-0290

Genes

VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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VKORC1 haplotypes and their impact on the inter-individual and inter-ethnical variability of oral anticoagulation.PMID 16270629Read ↗

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