Article
Current pharmacogenetic developments in oral anticoagulation therapy: the influence of variant VKORC1 and CYP2C9 alleles.
Thrombosis and haemostasis - 1 Sept 2007
Oldenburg Johannes, Bevans Carville G, Fregin Andreas, Geisen Christof, Müller-Reible Clemens, Watzka Matthias
Abstract excerpt
For decades coumarins have been the most commonly prescribed drugs for therapy and prophylaxis of thromboembolic conditions. Despite the limitation of their narrow therapeutic dosage window, the broad variation of intra- and inter-individual drug requirement, and the relatively high incidence of...
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