Article
Influence of carriage of hemoglobin AS and the Fc gamma receptor IIa-R131 allele on levels of immunoglobulin G2 antibodies to Plasmodium falciparum merozoite antigens in Gabonese children.
The Journal of infectious diseases - 1 Dec 2005
Ntoumi Francine, Flori Laurence, Mayengue Pembe Issamou, Matondo Maya Davy W, Issifou Saadou, Deloron Philippe, Lell Bertrand, Kremsner Peter G, Rihet Pascal
Abstract excerpt
BACKGROUND: To extend our previous findings showing an imbalanced distribution of immunoglobulin G2 (IgG2) antibodies to Plasmodium falciparum merozoite surface protein 2 (MSP2) and a higher frequency of infection with multiple P. falciparum strains in Gabonese children with sickle cell trait (hemoglobin AS), human Fc gamma receptor (Fc gamma R) IIa (CD32) polymorphism and the rate of in vitro invasion of red...
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