Article
FcgammaRIIa (CD32) polymorphism and anti-malarial IgG subclass pattern among Fulani and sympatric ethnic groups living in eastern Sudan.
Malaria journal - 13 Mar 2009
Nasr Amre, Iriemenam Nnaemeka C, Giha Hayder A, Balogun Halima A, Anders Robin F, Troye-Blomberg Marita, ElGhazali Gehad, Berzins Klavs
Abstract excerpt
BACKGROUND: A SNP at position 131, in the FcgammaRIIa gene, affects the binding of the different IgG subclasses and may influence the clinical variation seen in patients with falciparum malaria. This study confirms and extends previous findings, analysing the FcgammaRIIa (CD32) polymorphism in relation to the IgG subclass distribution seen among two sympatric tribes living in eastern Sudan, characterized by...
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