Article
Gene mutations in apical hypertrophic cardiomyopathy.
Circulation - 1 Nov 2005
Arad Michael, Penas-Lado Manual, Monserrat Lorenzo, Maron Barry J, Sherrid Mark, Ho Carolyn Y, Barr Scott, Karim Ahmad, Olson Timothy M, Kamisago Mitsohiro, Seidman J G, Seidman Christine E
Abstract excerpt
BACKGROUND: Nonobstructive hypertrophy localized to the cardiac apex is an uncommon morphological variant of hypertrophic cardiomyopathy (HCM) that often is further distinguished by distinct giant negative T waves and a benign clinical course. The genetic relationship between HCM with typical hypertrophic morphology versus isolated apical hypertrophy is incompletely understood. METHODS AND RESULTS: Genetic cause...
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