Genotype and arrhythmic risk in patients with apical hypertrophic cardiomyopathy.

doi:10.1136/heartjnl-2024-325218

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Genotype and arrhythmic risk in patients with apical hypertrophic cardiomyopathy.

Heart (British Cardiac Society) - 26 Aug 2025

Jeong Joo Hee, Kim Hwajung, Hwang Sung Ho, Seo Chang-Ok, Kim Yeji, Lee Hyoung Seok, Kim Yun Gi, Shim Jaemin, Kim Young-Hoon, Kim So Ree, Cho Dong-Hyuk, Kim Mi-Na, Park Seong-Mi, Choi Young, Choi Jong-Il

Abstract excerpt

BACKGROUND: Apical hypertrophic cardiomyopathy (HCM) is a rare variant of HCM, often considered to have a benign prognosis. This study aimed to compare the clinical characteristics and genetic predisposition of apical HCM with non-apical HCM. METHODS: We included 195 patients with HCM who underwent next-generation sequencing at two tertiary centres in South Korea (2017-2024). The primary outcome was a composite...

Read the complete abstract on PubMed

Topics

Humans
Male
Female
Cardiomyopathy, Hypertrophic
Middle Aged
Republic of Korea

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Genetic Predisposition to Disease

Arrhythmias, Cardiac

Aged

Risk Assessment

Risk Factors

Genotype

Retrospective Studies

Cardiac Myosins

Myosin Heavy Chains

Carrier Proteins

High-Throughput Nucleotide Sequencing

Phenotype

Source

Open in PubMed

Identifiers

PMID: 40194828
DOI: 10.1136/heartjnl-2024-325218

Genes

MYBPC3
MYH7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genotype and arrhythmic risk in patients with apical hypertrophic cardiomyopathy.PMID 40194828Read ↗

Unravelling the Genotype of the Apical Variant of Hypertrophic Cardiomyopathy in a Swedish Cohort.Semantic proximity Read ↗

Phenotype, genotype and prognosis of apical hypertrophic cardiomyopathies: a French multicentric cohort.Semantic proximity Read ↗

Sarcomere protein gene mutations in patients with apical hypertrophic cardiomyopathy.Semantic proximity Read ↗

Prevalence, characteristics, and natural history of apical phenotype in a large cohort of patients with hypertrophic cardiomyopathy.Semantic proximity Read ↗

Differential contributions of sarcomere and mitochondria-related multigene variants to the endophenotype of hypertrophic cardiomyopathy.Semantic proximity Read ↗

Unveiling Clinical and Genetic Distinctions in Pure-Apical Versus Distal-Dominant Apical Hypertrophic Cardiomyopathy.Semantic proximity Read ↗

Genotype-Phenotype Correlations in Apical Variant Hypertrophic Cardiomyopathy.Semantic proximity Read ↗

Comparison of the prevalence, clinical features, and long-term outcomes of midventricular hypertrophy vs apical phenotype in patients with hypertrophic cardiomyopathy.Semantic proximity Read ↗

Cardiomyopathy in Northwestern Mexico: Clinical Spectrum, Morphological Variants, and Sarcomere Gene Mutations.Semantic proximity Read ↗

Genetic determinants of the phenotype in a Swedish cohort of patients with hypertrophic cardiomyopathySemantic proximity Read ↗

Clinical exome sequencing unravels the diverse spectrum of genetic heterogeneity and genotype-phenotype correlations in hypertrophic cardiomyopathy.Semantic proximity Read ↗

A Wide and Specific Spectrum of Genetic Variants and Genotype-Phenotype Correlations Revealed by Next-Generation Sequencing in Patients with Left Ventricular Noncompaction.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.