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Article

Genotype-Phenotype Correlations in Apical Variant Hypertrophic Cardiomyopathy.

Congenital heart disease - 1 Jan 2000

Towe Eric C, Bos J Martijn, Ommen Steve R, Gersh Bernard J, Ackerman Michael J

Abstract excerpt

OBJECTIVE: Hypertrophic cardiomyopathy is underscored by profound phenotypic and genotypic heterogeneity. Echocardiographically, hypertrophic cardiomyopathy can be categorized into four morphological subtypes: reverse curve, sigmoidal, neutral contour, and apical variant. Previous studies indicate that reverse curve hypertrophic cardiomyopathy is the strongest predictor of a positive genetic test. Little is known...

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Share to Cardiomyopathy and Myosin Studies
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25495007
DOI: 10.1111/chd.12242

Genes

MYBPC3
MYH7
ACTC1
TPM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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