Article
Mast cells in ongoing acute rejection: increase in number and expression of a different phenotype in rat heart transplants.
Transplantation - 15 Jun 2002
Zweifel Martin, Hirsiger Hans, Matozan Katja, Welle Monika, Schaffner Thomas, Mohacsi Paul
Abstract excerpt
BACKGROUND: Mast cells (MC) are resident in healthy hearts and play important physiological and pathophysiological roles. In the transplanted heart, correlations have been found between MC number and the severity of rejection episodes, the intensity of chronic inflammation, and allograft arteriosclerotic changes. However, not much emphasis has been placed on the fact that resident donor MC, and infiltrating...
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