Article
Killer immunoglobulin-like receptor genotype in immune-mediated bone marrow failure syndromes.
Experimental hematology - 1 Nov 2005
Howe Evan C, Wlodarski Marcin, Ball Edward J, Rybicki Lisa, Maciejewski Jaroslaw P
Abstract excerpt
OBJECTIVE: Recent reports have shown that killer immunoglobulin-like receptors (KIR) and KIR ligand (KIR-L) genotype play a role in the pathophysiology of autoimmune disorders. Certain KIR/KIR-L combinations might convey a predisposition to immune-mediated bone marrow failure. Examining the genotypic makeup of human leukocyte antigen (HLA) class I (KIR-L) and KIR in patients with hematologic disorders could offer...
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