Article
Risk of selecting K65R in antiretroviral-naive HIV-infected individuals with chronic hepatitis B treated with adefovir.
AIDS (London, England) - 18 Nov 2005
Sheldon Julie A, Corral Angélica, Rodés Berta, Mauss Stefan, Rockstroh Juergen, Berger Florian, Schwarze-Zander Carolynne, Soriano Vincent
Abstract excerpt
Seven antiretroviral-naive HIV-infected individuals with chronic hepatitis B treated with adefovir for longer than 6 months were assessed. Using bulk population sequencing and a sensitive limiting dilution analysis, the selection of K65R or other resistance mutations did not occur in HIV, suggesting that adefovir can be confidently used as hepatitis B virus (HBV) therapy in HIV/HBV-co-infected patients who do not...
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