Article
Effect of the apolipoprotein E epsilon4 allele on the efficacy and tolerability of galantamine in the treatment of Alzheimer's disease.
Dementia and geriatric cognitive disorders - 1 Jan 2006
Suh Guk-Hee, Jung Hee Yeon, Lee Chang Uk, Oh Byoung Hoon, Lee Sang-Kyu, Lee NamJin, Kim JaeHyun, Kee Baik Seok, Ko Daekwan, Kim Young-Hoon, Ju Young-Su, Hong InJa, Choi Sungku
Abstract excerpt
OBJECTIVE: To investigate the effect of the apolipoprotein E (ApoE) epsilon4 allele on the efficacy and tolerability of galantamine treatment. METHODS: A total of 202 patients with mild to moderate Alzheimer's disease participated in a 16-week, prospective, multi-center, randomized, double-blind galantamine trial in a Korean population. Patients were assessed at baseline and after 4, 8 and 16 weeks of randomized...
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