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Article

Cross-clade recognition and neutralization by the V3 region from clade C human immunodeficiency virus-1 envelope.

Vaccine - 5 Jun 2006

Wu Lan, Yang Zhi-Yong, Xu Ling, Welcher Brent, Winfrey Sarah, Shao Yiming, Mascola John R, Nabel Gary J

Abstract excerpt

To understand the cross-reactivity of antibodies directed against variable regions of human immunodeficiency virus-1 (HIV-1) envelope (Env), chimeric immunogens were prepared from different clades with modifications in variable regions, and the resulting neutralizing antibody response was evaluated. The V3-specific neutralization activity induced by a clade B immunogen was limited to clade B viruses and was...

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Identifiers

PMID: 16690178
DOI: 10.1016/j.vaccine.2006.03.083

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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