Article
Cytokine gene polymorphism in sympathetic ophthalmia.
Investigative ophthalmology & visual science - 1 Nov 2005
Atan Denize, Turner Steve J, Kilmartin Dara J, Forrester John V, Bidwell Jeff, Dick Andrew D, Churchill Amanda J
Abstract excerpt
PURPOSE: Sympathetic ophthalmia (SO) is a prototypical autoimmune disease in which injury to one eye causes sight-threatening inflammation in the otherwise normal contralateral eye. Previous work found that human leukocyte antigen alleles HLA-DRB1*04 and DQA1*03 are markers of increased susceptibility and severity in British and Irish patients. Evidence is accumulating that single nucleotide polymorphisms (SNPs)...
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