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Article

Structure and functional analysis of the fungal galectin CGL2.

Structure (London, England : 1993) - 1 Apr 2004

Walser Piers J, Haebel Peter W, Künzler Markus, Sargent David, Kües Ursula, Aebi Markus, Ban Nenad

Abstract excerpt

Recognition of and discrimination between potential glyco-substrates is central to the function of galectins. Here we dissect the fundamental parameters responsible for such selectivity by the fungal representative, CGL2. The 2.1 A crystal structure of CGL2 and five substrate complexes reveal that this prototype galectin achieves increased substrate specificity by accommodating substituted oligosaccharides of the...

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Identifiers

PMID: 15062091
DOI: 10.1016/j.str.2004.03.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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