Article
Structure and functional analysis of the fungal galectin CGL2.
Structure (London, England : 1993) - 1 Apr 2004
Walser Piers J, Haebel Peter W, Künzler Markus, Sargent David, Kües Ursula, Aebi Markus, Ban Nenad
Abstract excerpt
Recognition of and discrimination between potential glyco-substrates is central to the function of galectins. Here we dissect the fundamental parameters responsible for such selectivity by the fungal representative, CGL2. The 2.1 A crystal structure of CGL2 and five substrate complexes reveal tha...
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