Selection of a Borrelia burgdorferi antigenic variant by cultivation in the presence of increasing amounts of homologous immune serum.

doi:10.1016/0378-1097(92)90534-u

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Article

Selection of a Borrelia burgdorferi antigenic variant by cultivation in the presence of increasing amounts of homologous immune serum.

FEMS microbiology letters - 1 Apr 1992

Cinco M

Abstract excerpt

This investigation was undertaken to select antigenic variants of a Borrelia burgdorferi strain in vitro. The original strain BITS was cultivated in BSK medium supplemented with increasing concentrations of homologous hyperimmune serum raised in rabbits. After a few serial passages starting from...

Topics

Antibodies, Bacterial
Antibody Specificity
Antigenic Modulation
Borrelia burgdorferi Group
Genetic Variation
Selection, Genetic
Serial Passage

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