Selection of a Borrelia burgdorferi antigenic variant by cultivation in the presence of increasing amounts of homologous immune serum.

Abstract excerpt

This investigation was undertaken to select antigenic variants of a Borrelia burgdorferi strain in vitro. The original strain BITS was cultivated in BSK medium supplemented with increasing concentrations of homologous hyperimmune serum raised in rabbits. After a few serial passages starting from a subinhibitory serum dilution of 1:800 in BSK up to 1:200, a variant named BITSv was obtained; it grew abundantly like...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Antibodies, Bacterial
• Share to Antibody Specificity
• Share to Borrelia burgdorferi Group