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Article

[Analysis of mutation mechanisms in human mitochondrial DNA].

Molekuliarnaia biologiia - 1 Jan 2000

Kornienko I V, Maliarchuk B A

Abstract excerpt

The reasons of high level of human mitochondrial DNA (mtDNA) variability remain to be largely unclear. We analyze here three probable mechanisms of mutagenesis leading to generation of mtDNA nucleotide substitutions: (1) deamination of DNA bases; (2) tautomeric migrations of protons in nitrous bases; and (3) hydrolysis of glycoside link between DNA bases and carbohydrate residue on the background of free radical...

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PMID: 16240720

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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