Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Rapid detection of chromosomal aneuploidies in uncultured amniocytes by multiplex ligation-dependent probe amplification (MLPA)

1 Jan 2005

Abstract excerpt

OBJECTIVE: To test whether multiplex ligation-dependent probe amplification (MLPA) can be used for the detection of aneuploidy of chromosomes 13, 18, 21, X, and Y in uncultured amniocytes. METHODS: We performed a prospective study based on 527 amniotic fluid samples. Chromosome copy numbers were determined by analysing the relative amount of PCR product of chromosome-specific MLPA probes. Results were available...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Syndromes and Imprinting
Share to Genomic variations and chromosomal abnormalities
Share to Prenatal Screening and Diagnostics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16231311
DOI: 10.1002/pd.1247

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Rapid detection of chromosomal aneuploidies in uncultured amniocytes by multiplex ligation-dependent probe amplification (MLPA)PMID 16231311Read ↗

Multiplex Ligation‐dependent Probe Amplification (MLPA) as a stand‐alone test for rapid aneuploidy detection in amniotic fluid cellsSemantic proximity Read ↗

Comparison of Multiplex Ligation-Dependent Probe Amplification and Karyotyping in Prenatal DiagnosisSemantic proximity Read ↗

Rapid aneuploidy detection with multiplex ligation-dependent probe amplification: a prospective study of 4000 amniotic fluid samplesSemantic proximity Read ↗

Rapid aneuploidy diagnosis by multiplex ligation-dependent probe amplification and array comparative genomic hybridization in pregnancy with major congenital malformationsSemantic proximity Read ↗

Multiplex ligation‐dependent probe amplification (MLPA) and prenatal diagnosisSemantic proximity Read ↗

The development of a rapid assay for prenatal testing of common aneuploidies and microdeletion syndromesSemantic proximity Read ↗

Prenatal detection of unbalanced chromosomal rearrangements by array CGHSemantic proximity Read ↗

A large‐scale evaluation of amnio‐PCR for the rapid prenatal diagnosis of fetal trisomySemantic proximity Read ↗

MLPA as a screening method of aneuploidy and unbalanced chromosomal rearrangements in spontaneous miscarriagesSemantic proximity Read ↗

Rapid prenatal diagnosis using uncultured amniocytes and oligonucleotide array CGHSemantic proximity Read ↗

Prenatal diagnosis and molecular cytogenetic characterization of low-level true mosaicism for trisomy 21 using uncultured amniocytesSemantic proximity Read ↗

Mosaic Trisomy 9 at Amniocentesis: Prenatal Diagnosis and Molecular Genetic AnalysesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.