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Article

Multiplex Ligation‐dependent Probe Amplification (MLPA) as a stand‐alone test for rapid aneuploidy detection in amniotic fluid cells

16 Oct 2008

Abstract excerpt

OBJECTIVE: This study aimed to determine the diagnostic application of multiplex ligation-dependent probe amplification (MLPA) as a stand-alone test for targeted detection of common chromosomal aneuploidies (i.e. 13, 18, 21, X and Y) in amniotic fluid cells in routine prenatal clinical practice. METHODS: In this evaluation study, the MLPA test using kit P095 was performed on 1000 consecutive amniotic fluid...

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Share to Genomic variations and chromosomal abnormalities
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Share to Prenatal Screening and Diagnostics

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PMID: 18925610
DOI: 10.1002/pd.2111

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