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Rapid prenatal diagnosis using uncultured amniocytes and oligonucleotide array CGH

15 Sept 2008

Abstract excerpt

OBJECTIVE: Oligonucleotide-based array comparative genomic hybridization (array CGH) is an established method for detecting chromosomal abnormalities. Here, we explored the feasibility of using DNA extracted from uncultured amniocytes in amniotic fluid for array CGH on an oligonucleotide array platform. METHODS: Fifteen fetuses from 14 ongoing pregnancies were studied by array CGH on targeted oligonucleotide...

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PMID: 18792925
DOI: 10.1002/pd.2087

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