Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A large‐scale evaluation of amnio‐PCR for the rapid prenatal diagnosis of fetal trisomy

1 Feb 2001

Abstract excerpt

OBJECTIVE: Traditional chromosome preparation from amniotic fluid samples often involves lengthy culture procedures in order to obtain cells for analysis. Multiplex quantitative fluorescent polymerase chain reaction (PCR) is a new molecular biological technique capable of quantifying in-situ DNA without the need for cell culture. Our objective was to test the reliability of PCR using fetal DNA from amniotic fluid...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Genomic variations and chromosomal abnormalities
Share to Prenatal Screening and Diagnostics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 11251918
DOI: 10.1046/j.1469-0705.2001.00340.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A large‐scale evaluation of amnio‐PCR for the rapid prenatal diagnosis of fetal trisomyPMID 11251918Read ↗

Rapid prenatal diagnosis of aneuploidy by quantitative fluorescent PCR on fetal samples from mothers at high risk for chromosome disordersSemantic proximity Read ↗

Rapid Prenatal Diagnosis of Aneuploidy Using Quantitative Fluorescence-PCR (QF-PCR)Semantic proximity Read ↗

Comparison of Multiplex Ligation-Dependent Probe Amplification and Karyotyping in Prenatal DiagnosisSemantic proximity Read ↗

The introduction of QF-PCR in prenatal diagnosis of fetal aneuploidies: time for reconsiderationSemantic proximity Read ↗

Prenatal diagnosis of common aneuploidies using quantitative fluorescent PCRSemantic proximity Read ↗

Rapid prenatal diagnosis of common chromosome aneuploidies by QF‐PCR, results of 9 years of clinical experienceSemantic proximity Read ↗

Mosaic Trisomy 9 at Amniocentesis: Prenatal Diagnosis and Molecular Genetic AnalysesSemantic proximity Read ↗

Development and implementation of a new rapid aneuploidy diagnostic service within the UK National Health Service and implications for the future of prenatal diagnosis.Semantic proximity Read ↗

Fetal nuchal translucency scan and early prenatal diagnosis of chromosomal abnormalities by rapid aneuploidy screening: observational studySemantic proximity Read ↗

Rapid detection of chromosome aneuploidies by quantitative fluorescence PCR: first application on 247 chorionic villus samplesSemantic proximity Read ↗

Rapid and simple prenatal diagnosis of common chromosome disorders: advantages and disadvantages of the molecular methods FISH and QF-PCRSemantic proximity Read ↗

Detection of Chromosome Aberrations in the Second Trimester Using Genetic Amniocentesis: Experience During 1995-2004Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.