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High-Level Drug-Resistant Mutations among HIV-1 Subtype A6 and CRF02_AG in Kazakhstan.

Viruses - 21 Jun 2023

Sanaubarova Ainur, Pujol-Hodge Emma, Dzissyuk Natalya, Lemey Philippe, Vermund Sten H, Leigh Brown Andrew J, Ali Syed

Abstract excerpt

HIV incidence in Kazakhstan increased by 73% between 2010 and 2020, with an estimated 35,000 people living with HIV (PLHIV) in 2020. The development of antiretroviral drug resistance is a major threat to effective antiretroviral therapy (ART), yet studies on the prevalence of drug resistance in Kazakhstan are sparse. In this study on the molecular epidemiology of HIV in Kazakhstan, we analyzed 968 partial HIV-1...

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Anti-HIV Agents
Drug Resistance, Viral
Genotype
HIV-1
HIV Infections

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PMID: 37515095
DOI: 10.3390/v15071407
PMCID: PMC10384832

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