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Article

Cytochrome P4501A1 and glutathione S transferase gene polymorphisms in patients with aplastic anemia in India.

Acta haematologica - 1 Jan 2005

Poonkuzhali B, Shaji R V, Salamun D E, George B, Srivastava A, Chandy M

Abstract excerpt

The etiology of acquired aplastic anemia (AA) in most patients remains unclear. It is believed that patients with a reduced ability to detoxify environmental toxins are at increased risk of developing AA. Cytochrome P450 (CYP450) and glutathione S transferase (GST) are the major phase I and phase II xenobiotic-metabolizing enzymes. We analyzed the impact of the polymorphisms in CYP4501A1 and GSTM1 and GSTT1 genes...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP1A1

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Share to Polymorphism, Genetic

Source

Identifiers

PMID: 16227674
DOI: 10.1159/000087885

Genes

GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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