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Article

Genetic susceptibility to type 1 diabetes.

Current opinion in immunology - 1 Dec 2005

Maier Lisa M, Wicker Linda S

Abstract excerpt

The recent discovery of PTPN22 as a novel susceptibility gene in human type 1 diabetes and continued progress in defining genes in animal models of the disease mark a fruitful period in the field of type 1 diabetes genetics. In addition, the similarities of the genetic and functional aspects across species have been substantiated. Future genome-wide association studies will reveal more loci, each providing a...

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Topics

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Share to Antigens, Differentiation
Share to CTLA-4 Antigen
Share to Interleukin-2 Receptor alpha Subunit

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Major Histocompatibility Complex

Share to Mice, Inbred NOD

Share to Protein Tyrosine Phosphatase, Non-Receptor Type 1

Share to Protein Tyrosine Phosphatase, Non-Receptor Type 22

Share to Receptors, Interleukin

Source

Identifiers

PMID: 16226440
DOI: 10.1016/j.coi.2005.09.013

Genes

PTPN22

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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