Article
HdaA, a major class 2 histone deacetylase of Aspergillus nidulans, affects growth under conditions of oxidative stress.
Eukaryotic cell - 1 Oct 2005
Tribus Martin, Galehr Johannes, Trojer Patrick, Brosch Gerald, Loidl Peter, Marx Florentine, Haas Hubertus, Graessle Stefan
Abstract excerpt
Histone deacetylases (HDACs) catalyze the removal of acetyl groups from the epsilon-amino group of distinct lysine residues in the amino-terminal tail of core histones. Since the acetylation status of core histones plays a crucial role in fundamental processes in eukaryotic organisms, such as replication and regulation of transcription, recent research has focused on the enzymes responsible for the...
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