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Article

Mad2beta, an alternative variant of Mad2 reducing mitotic arrest and apoptosis induced by adriamycin in gastric cancer cells.

Life sciences - 16 Feb 2006

Yin Fang, Du Yulei, Hu Wenhua, Qiao Taidong, Ding Jie, Wu Kaichun, Liu Zhiguo, Fan Daiming

Abstract excerpt

Mad2beta is an alternative splicing variant of spindle checkpoint gene mad2, which was previously found by us and was related to the drug resistance in gastric cancer cells. In this paper, we explored the molecular mechanisms that Mad2beta variant promoted the formation of multidrug resistance in gastric cancer cells. We found that Mad2beta variant was detected only in the two human drug resistant gastric cancer...

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Identifiers

PMID: 16214181
DOI: 10.1016/j.lfs.2005.06.034

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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