Article
C2-ceramide exhibits antiproliferative activity and potently induces apoptosis in endometrial carcinoma.
Oncology reports - 1 Nov 2005
Takai Noriyuki, Ueda Tami, Kawano Yasushi, Nishida Masakazu, Nasu Kaei, Narahara Hisashi
Abstract excerpt
The purpose of the present study was to investigate the effects of an exogenously administered cell-permeable synthetic ceramide analogue, C(2)-ceramide (N-acetyl-sphingosine) on the growth, cell cycle, and death of Ishikawa human endometrial carcinoma cells. We investigated the effects of C(2)-ceramide on Ishikawa endometrial cancer cell lines in vitro. The cells were treated with C(2)-ceramide, and its effects...
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