Article
CBHA is a family of hybrid polar compounds that inhibit histone deacetylase, and induces growth inhibition, cell cycle arrest and apoptosis in human endometrial and ovarian cancer cells.
Oncology - 1 Jan 2006
Takai Noriyuki, Ueda Tami, Nishida Masakazu, Nasu Kaei, Matsuda Kaho, Kusumoto Mamiko, Narahara Hisashi
Abstract excerpt
OBJECTIVES: We investigated the effect of a novel synthesized histone deacetylase inhibitor (HDACI), CBHA, on three endometrial cancer cell lines, two ovarian cancer cell lines, and normal human endometrial epithelial cells. METHODS: Endometrial and ovarian cancer cells were treated with various...
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