Article
CD4+CD25+ regulatory T cells in the peripheral blood of patients with breast cancer and non-small cell lung cancer.
Oncology reports - 1 Nov 2005
Okita Riki, Saeki Toshiaki, Takashima Shigemitsu, Yamaguchi Yoshiyuki, Toge Tetsuya
Abstract excerpt
It is well known that immunosuppression may contribute to the progression and chemotherapy-resistance of cancer. Recent studies have demonstrated that lymphocytes with the phenotype of CD4+CD25+ regulatory T cells (T-regs) contribute to immune dysfunction in cancer patients, and a relative increase in CD4+CD25+ regulatory T cells is related to immunosuppression and tumor progression in patients with some...
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