Article
Clinical significance of the frequency of regulatory T cells in regional lymph node lymphocytes as a prognostic factor for non-small-cell lung cancer.
Lung cancer (Amsterdam, Netherlands) - 1 Sept 2013
Hanagiri Takeshi, Shigematsu Yoshiki, Shinohara Shinji, Takenaka Masaru, Oka Sohich, Chikaishi Yasuhiro, Nagata Yoshika, Iwata Teruo, Uramoto Hidetaka, So Tomoko, Tanaka Fumihiro
Abstract excerpt
BACKGROUND: Regulatory T cells (Tregs) are potent immunosuppressive cells that play a crucial role in tumor immune escape. The purpose of the present study was to evaluate the prognostic significance of the frequency of CD4+CD25+Foxp3+ Tregs in the regional lymph node lymphocytes (RLNL) and perip...
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