Article
Nuclear chromatin patterns in 3 glucocorticoid-resistant RPMI 8226 human myeloma cell sub-lines: correlations with cell growth and immunological phenotype.
Cancer biology & therapy - 1 Aug 2005
Genty Vincent, El-Khoury Victoria, Liautaud-Roger Françoise, Dine Gérard, Dufer Jean
Abstract excerpt
Nuclear morphological alterations associated with glucocorticoid resistance in human myeloma were evaluated by image cytometry in three human myeloma RPMI 8226 cell sub-lines. Resistance was induced by drug selection using prednisone (8226p), methylprednisolone (8226m) and dexamethasone (8226d), respectively. All these three cell sub lines displayed significant glucocorticoid-resistance without cross-resistance...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
