Article
Heterogeneity of biofilms formed by nonmucoid Pseudomonas aeruginosa isolates from patients with cystic fibrosis.
Journal of clinical microbiology - 1 Oct 2005
Lee Baoleri, Haagensen Janus A J, Ciofu Oana, Andersen Jens Bo, Høiby Niels, Molin Søren
Abstract excerpt
Biofilms are thought to play a key role in the occurrence of lung infections by Pseudomonas aeruginosa in patients with cystic fibrosis (CF). In this study, 20 nonmucoid P. aeruginosa isolates collected during different periods of chronic infection from eight CF patients were assessed with respect to phenotypic changes and in vitro biofilm formation. The physiological alterations were associated with a loss of...
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