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Article

Conditions associated with the cystic fibrosis defect promote chronic Pseudomonas aeruginosa infection.

American journal of respiratory and critical care medicine - 1 Apr 2014

Staudinger Benjamin J, Muller Jocelyn Fraga, Halldórsson Skarphéðinn, Boles Blaise, Angermeyer Angus, Nguyen Dao, Rosen Henry, Baldursson Olafur, Gottfreðsson Magnús, Guðmundsson Guðmundur Hrafn, Singh Pradeep K

Abstract excerpt

RATIONALE: Progress has been made in understanding how the cystic fibrosis (CF) basic defect produces lung infection susceptibility. However, it remains unclear why CF exclusively leads to chronic infections that are noninvasive and highly resistant to eradication. Although biofilm formation has been suggested as a mechanism, recent work raises questions about the role of biofilms in CF. OBJECTIVES: To learn how...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24467627
DOI: 10.1164/rccm.201312-2142OC
PMCID: PMC4225830

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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