Bacterial Adhesion: Genetics, Biogenesis, and Role in Pathogenesis of Fimbrial Adhesins of Escherichia coli

Abstract excerpt

Microbial pathogenicity is a complex phenomenon encompassing many varied mechanisms. There are, however, several common strategies that pathogenic organisms use to sustain themselves and overcome host barriers. In one of these strategies, the first step is the firm adhesion of the microorganism to host cells. Adhesion is frequently mediated by organelles called fimbriae. A surprising variety of fimbrial adhesins...

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