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Article

Overexpression of the ZIP1 zinc transporter induces an osteogenic phenotype in mesenchymal stem cells.

Bone - 1 Feb 2006

Tang Zhihui, Sahu Surasri Nandan, Khadeer Mohammed Abdul, Bai Guang, Franklin Renty B, Gupta Anandarup

Abstract excerpt

Zinc is an essential trace element that is involved in diverse metabolic and signaling pathways. Zinc deficiency is associated with retardation of bone growth. Previous in vitro studies have suggested a direct effect of zinc on both the proliferation and differentiation of osteoblast-like cells. However, the mechanisms for uptake of zinc into osteoblasts have not been examined in detail. Several families of zinc...

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Identifiers

PMID: 16203195
DOI: 10.1016/j.bone.2005.08.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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