Article
Association of refractory complex partial seizures with a polymorphism of ApoE genotype.
Journal of cellular and molecular medicine - 1 Jan 2000
Sporis Davor, Sertic Jadranka, Henigsberg Neven, Mahovic Darija, Bogdanovic Nenad, Babic Tomislav
Abstract excerpt
Apolipoprotein E (ApoE) is a constituent of many types of lipoproteins that play a role in metabolism of cholesterol and lipids in the body as well as in the brain. ApoE is synthesised in astrocytes and microglia and enter to neurons through LDL, LRP and VLDL receptors. Recently it was shown that ApoE is also produced in neurons. ApoE has a role in modulating learning and memory, structural plasticity,...
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