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Article

Lactation induces increases in the RANK/RANKL/OPG system in maxillary bone.

Bone - 1 May 2018

Macari Soraia, Sharma Lavanya A, Wyatt Amanda, da Silva Janine Maíra, Dias George J, Silva Tarcília A, Szawka Raphael E, Grattan David R

Abstract excerpt

The underlying causes of maxillary bone loss during lactation remain poorly understood. We evaluated the impact of lactation on physiological and mechanically-induced alveolar bone remodeling. Nulliparous non-lactating (N-LAC) and 21-day lactating (LAC) mice underwent mechanically-induced bone remodeling by orthodontic tooth movement (OTM). Micro-computed tomography (microCT) was performed in the maxilla, femur...

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Identifiers

PMID: 29382610
DOI: 10.1016/j.bone.2018.01.032

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