Article
The distribution of FSH receptor isoforms is related to basal FSH levels in subfertile women with normal menstrual cycles.
Human reproduction (Oxford, England) - 1 Feb 2006
de Koning C H, Benjamins T, Harms P, Homburg R, van Montfrans J M, Gromoll J, Simoni M, Lambalk C B
Abstract excerpt
BACKGROUND: Recently a polymorphic variant of the FSH receptor in which amino acid asparagine (Asn) at position 680 is replaced by serine (Ser) was found. This is associated with higher FSH levels in the early follicular phase and an increased FSH requirement to obtain follicular response in IVF patients. The aim of our study was to test the hypothesis that this receptor isoform occurs more often in regularly...
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