Article
Polymorphism of the FSH receptor and ovarian response to FSH.
Annales d'endocrinologie - 1 Jun 2007
Wunsch A, Sonntag B, Simoni M
Abstract excerpt
Follicle-stimulating hormone (FSH) is a key factor in human reproduction. FSH activates its receptor (FSHR) located exclusively on Sertoli cells in the testis and granulosa cells in the ovary. Two common single nucleotide polymorphisms (SNP) within exon 10 of the human FSHR gene result in two almost equally common allelic variants exhibiting threonine (Thr) or alanine (Ala) at position 307 in the hinge region,...
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