Article
Divergence, recombination and retention of functionality during protein evolution.
Human genomics - 1 Sept 2005
Xu Yanlong O, Hall Randall W, Goldstein Richard A, Pollock David D
Abstract excerpt
We have only a vague idea of precisely how protein sequences evolve in the context of protein structure and function. This is primarily because structural and functional contexts are not easily predictable from the primary sequence, and evaluating patterns of evolution at individual residue positions is also difficult. As a result of increasing biodiversity in genomics studies, progress is being made in detecting...
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