Article
Serotonin deficiency shortens the duration of forward movement in Caenorhabditis elegans.
Bioscience, biotechnology, and biochemistry - 1 Sept 2005
Wakabayashi Tokumitsu, Osada Takashi, Shingai Ryuzo
Abstract excerpt
Serotonin has been implicated in numerous behaviors in a wide variety of animals. We examined the effect of serotonin deficiency, induced by genetic perturbations and cell ablations, on the duration of Caenorhabditis elegans forward movement. Mutants with defective serotonin biosynthesis or worms with ablated serotonergic neurons showed a markedly decreased duration of forward movement, suggesting involvement of...
Topics
- Animals
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Locomotion
- Mutation
- Serotonin
- Time Factors
