Article
Association of HLA class I and class II alleles with susceptibility to endometriosis.
Human immunology - 1 Nov 2002
Kitawaki Jo, Obayashi Hiroshi, Kado Noriko, Ishihara Hiroaki, Koshiba Hisato, Maruya Etsuko, Saji Hiroh, Ohta Mitsuhiro, Hasegawa Goji, Nakamura Naoto, Yoshikawa Toshikazu, Honjo Hideo
Abstract excerpt
Although the exact etiology of endometriosis is unclear, several lines of evidence support roles for both cell-mediated and humoral immunity in its pathogenesis. To assess the association between HLA genotypes and endometriosis, we investigated the frequencies of HLA-A, -B, -C, and -DRB1 antigens or alleles in 123 Japanese patients with endometriosis and 165 healthy women as controls. Significant positive...
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