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Development of a Liquid Biopsy Based Purely Quantitative Digital Droplet PCR Assay for Detection of MLH1 Promoter Methylation in Colorectal Cancer Patients

2021-03-08

Abstract excerpt

<h4>Background: </h4> MutL Homolog 1 (MLH1) promotor methylation is associated with microsatellite instability high colorectal cancer (CRC). The strong correlation between methylation status and cancer development and progression has led to a growing interest in the use of methylation markers in circulating tumor DNA (ctDNA) for early cancer detection and longitudinal monitoring. As cancer-specific DNA methylation...

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Literature Corpus work
860ad5da-fec3-5872-85a1-8a840ae9a637
DOI
10.21203/rs.3.rs-155375/v1
Open publication

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Development of a Liquid Biopsy Based Purely Quantitative Digital Droplet PCR Assay for Detection of MLH1 Promoter Methylation in Colorectal Cancer PatientsDOI 10.21203/rs.3.rs-155375/v1
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