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Article

Mutational analysis of the BRAF gene in human congenital and dysplastic melanocytic naevi

22 Sept 2005

Abstract excerpt

Eighteen congenital melanocytic naevi (CMN) from 17 patients and 18 dysplastic melanocytic naevi (DMN) from 18 patients were screened for mutations in the BRAF oncogene (present study) and the N-ras oncogene (in the course of two foregoing studies) by single-strand conformational polymorphism (SSCP)/sequencing analysis. BRAF mutations were demonstrated in both types of lesion. As a whole, 17 of 18 CMN (94.4%) and...

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PMID: 16179867
DOI: 10.1097/00008390-200510000-00008

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