Article
Gelatinase B C(-1562)T polymorphism in relation to ischaemic heart disease.
Scandinavian journal of clinical and laboratory investigation - 1 Jan 2005
Haberbosch W, Gardemann A
Abstract excerpt
OBJECTIVE: Matrix metalloproteinases, such as gelatinase B, are important in connective tissue remodelling processes associated with atherogenesis and plaque rupture. The T allele of the gelatinase B C((-1562)) T polymorphism has been reported to be associated with an almost 2-fold increase in promoter activity and with the extent of coronary artery disease (CAD). The aim of this study was to analyse the relation...
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