Article
Strategies for biology- and molecular-based treatment of myelodysplastic syndromes.
Current drug targets - 1 Sept 2005
Lindberg Eva Hellström
Abstract excerpt
The myelodysplastic syndromes (MDS) constitute a group of clonal stem cell disorders characterized by cytopenia, ineffective hematopoiesis, bone marrow dysplasia, and a risk of progression to acute myeloid leukemia (AML). Disease mechanisms can be divided into two main groups; those underlying the increased apoptosis of bone marrow progenitors, and those associated with progressive blast proliferation, and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
