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Article

The association of aldose reductase gene (AKR1B1) polymorphisms with diabetic neuropathy in adolescents.

Diabetic medicine : a journal of the British Diabetic Association - 1 Oct 2005

Donaghue K C, Margan S H, Chan A K F, Holloway B, Silink M, Rangel T, Bennetts B

Abstract excerpt

AIMS: Variants in the aldose reductase gene (AKR1B1) have been implicated in the development of diabetic retinopathy and nephropathy, with the most convincing data identifying a (CA)(n) repeat microsatellite allele (Z-2), which has a functional role in gene expression. In this study the association between polymorphisms in the AKR1B1 gene and diabetic neuropathy was investigated. METHODS: The pupillary response...

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Share to Adolescent
Share to Aldehyde Reductase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 1

Share to Diabetic Neuropathies

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Share to Polymorphism, Genetic

Share to Polymorphism, Restriction Fragment Length

Source

Identifiers

PMID: 16176189
DOI: 10.1111/j.1464-5491.2005.01631.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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