Article
Genetic variation and correlation of dietary response in an advanced intercross mouse line produced from two divergent growth lines.
Genetical research - 1 Jun 2005
Ehrich Thomas H, Kenney-Hunt Jane P, Pletscher L Susan, Cheverud James M
Abstract excerpt
Levels of human obesity have increased over the past 20 years worldwide, primarily due to changes in diet and activity levels. Although environmental changes are clearly responsible for the increasing prevalence of obesity, individuals may show genetic variation in their response to an obesogenic environment. Here, we measure genetic variation in response to a high-fat diet in a mouse model, an F16 Advanced...
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